In this infographic, find out how supplementing with probiotics and prebiotics can have an impact on people suffering from obesity and/or type 2 diabetes.
Modulating the intestinal microbiota could improve the health of people suffering from obesity and type 2 diabetes, in particular by supplementing with probiotics and/or prebiotics.
In fact, they can :
- Reduce intestinal permeability and bacterial translocation, thereby reducing LPS-induced inflammation.
- Increase short-chain fatty acids and the proportion of Bifidobacteria in the intestine, leading to a reduction in total cholesterol levels, lipogenesis, triglycerides, LDL and adiposity. All this leads to a reduced risk of developing cardiovascular disease.
Glossary
LPS: lipopolysaccharides. These are bacterial endotoxins found in the outer membrane of Gram-negative bacteria.It consists of a complex lipid to which a polysaccharide is attached.
SCFA: short-chain fatty acids. These are metabolites produced by certain bacteria in the intestinal microbiota in the colon. They include butyrate, propionate and acetate.
LDL: low-density lipoprotein. LDL enables cholesterol to be transported around the body. Elevated triglycerides and LDL cholesterol are associated with obesity. LDL is known as ‘bad cholesterol’ because too much of it is a cardiovascular risk factor.
References
Pictures: Freepik
