Development and manufacturing probiotics food supplements

1/ Sourcing of probiotic strains

Beyond the probiotic qualities of bacteria, all strains are not equal when it comes to the problem of stability. It is important to select the most resistant strains.
It is also necessary to consider adding supports and ingredients compatible with their good stability.

Lactobacillus

Lactobacillus casei, helveticus, rhamnosus, salivarius, reuteri…

Bifidobacterium

Bifidobacterium longum, bifidum, animalis lactis…

Yeast

Saccharomyces cerevisiae boulardii

Exden

Provide independent expertise to guarantee multi-sourcing

1/ Sourcing of probiotic strains

Beyond the probiotic qualities of bacteria, all strains are not equal when it comes to the problem of stability. It is important to select the most resistant strains.

It is also necessary to consider adding supports and ingredients compatible with their good stability.

Lactobacillus

Lactobacillus casei, helveticus, rhamnosus, salivarius, reuteri…

Bifidobacterium

Bifidobacterium longum, bifidum, animalis lactis…

Yeast

Saccharomyces cerevisiae boulardii

Exden

Provide independent expertise to guarantee multi-sourcing

2/ Development of your formulations

R&D programme management in the field of innovative delivery forms: finding solutions for a new type of powder, a new probiotic dispersion matrix, etc.
Stability tests on strains within complex mixtures – Stability study protocol.
Literature searches and scientific summaries

Exden

Dedicated network (Ingredients – Processing – Analytical – Scientific)
Controlled deadlines
Entire team dedicated to your development.

2/ Development of your formulations

R&D programme management in the field of innovative delivery forms: finding solutions for a new type of powder, a new probiotic dispersion matrix, etc.

Stability tests on strains within complex mixtures – Stability study protocol.

Literature searches and scientific summaries

Exden

Dedicated network (Ingredients – Processing – Analytical – Scientific)
Controlled deadlines
Entire team dedicated to your development.

3/ Manufacturing of your finished products

Probiotic bacteria are even more effective if the cells’ full capacities are restored once they are revived inside our bodies. To achieve this, it is essential to adapt the industrial environment in which live microorganisms are handled in order to limit loss of viability during the manufacturing process and promote the good stability of probiotics throughout the finished product life cycle.
Choosing the right delivery form and packaging is also very important in order to optimise the stability of probiotics over time.

Probiopack_Exden

EXDEN’s Probiopack™ concept guarantees a food supplement formula containing probiotic bacteria that have been validated, manufactured and controlled to meet stability requirements.
Probiopack™ is a specific process, resulting from almost 20 years of experience, that combines various strains within a matrix dedicated to the stability and revival of probiotic bacteria.
Probiopack™ guarantees reliable analytical controls, validated by microbiological expertise. It also includes support for the set-up and implementation of real-time stability studies.
It is important to choose the right delivery form to ensure the stability of strains. And the materials in contact with them are just as important. Probiopack™ provides a guarantee of content/container compatibility.

Exden

Responsiveness and Flexibility
R&D and manufacturing times controlled
Small and Medium production series to enable SMEs to access the extremely buoyant probiotics market.

Our additional services

Scientific documents : scientific and bibliographic summaries.
Regulatory compliance : formula audits, label corrections, submissions to authorities, etc.
Health claims support.
Technical documents : technical data sheets, certificates of analysis, etc.

3/ Manufacturing of your food supplements

Probiotic bacteria are even more effective if the cells’ full capacities are restored once they are revived inside our bodies. To achieve this, it is essential to adapt the industrial environment in which live microorganisms are handled in order to limit loss of viability during the manufacturing process and promote the good stability of probiotics throughout the finished product life cycle.

Choosing the right delivery form and packaging is also very important in order to optimise the stability of probiotics over time.

Probiopack_Exden

EXDEN’s Probiopack™ concept guarantees a food supplement formula containing probiotic bacteria that have been validated, manufactured and controlled to meet stability requirements.
Probiopack™ is a specific process, resulting from almost 20 years of experience, that combines various strains within a matrix dedicated to the stability and revival of probiotic bacteria.
Probiopack™ guarantees reliable analytical controls, validated by microbiological expertise. It also includes support for the set-up and implementation of real-time stability studies.
It is important to choose the right delivery form to ensure the stability of strains. And the materials in contact with them are just as important. Probiopack™ provides a guarantee of content/container compatibility.

Exden

Responsiveness and Flexibility
R&D and manufacturing times controlled
Small and Medium production series to enable SMEs to access the extremely buoyant probiotics market.

Our additional services

Scientific documents : scientific and bibliographic summaries.
Regulatory compliance : formula audits, label corrections, submissions to authorities, etc.
Health claims support.
Technical documents : technical data sheets, certificates of analysis, etc.