Unfortunately, we are not all equal to conceive. Many couples have fertility disorders and are turning to in vitro fertilization (IVF) to have a baby. However, the chances of success remain low.

Spanish researchers studied the subject. They have examined the endometrium which, long considered sterile, has in fact its own microbiota. After evaluating its impact on hormonal regulation, the researchers showed that its composition, different from the vaginal microbiota, seems to have its importance in the success of a pregnancy in fertile women candidates for IVF. Indeed, the success of an IVF would depend on the Lactobacillus proportion in the uterine cavity. Thereby, a bacterial community dominated by Lactobacilli would significantly promote implantation, pregnancy and birth, as opposed to a low Lactobacillus population.

These results highlight the importance of the local microbiota in the nesting process, suggesting an interesting track to explore, such as Lactobacillus supplementation that could help women get pregnant.

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Reference

MORENO I, CODONER FM, VIELLA F, VALBUENA D, MARTINEZ-BLANCH JF, JIMENEZ-ALMAZAN J, ALONSO R, ALAMA P, REMOHI J, PELLICER A, RAMON D, SIMON C. Evidence that the endometrial microbiota has an effect on implantation success or failure. Am J Obstet Gynecol. 2016, 215(6):684-703